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Bioorthogonal Chemistry: A Revolution in Chemical Biology
INTRODUCTION Life is built on chemistry, but until recently, chemistry had to be studied outside of living systems. The development of bioorthogonal chemistry has completely revolutionized this. Bioorthogonal chemistry refers to a class of specialized reactions that occur inside living organisms without interfering with natural biochemical processes.2 First introduced by Dr. Carolyn Bertozzi, Professor of…
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Unlocking the Secrets of Protein Misfolding: AlphaFold’s Role in Cardiovascular Disease
The release of AlphaFold 1 in 2018 achieved the first significant breakthrough, but it was AlphaFold 2 in 2020 that revolutionized the field, predicting protein structures with a level of accuracy that was previously impossible.